Colts vs Cardinals Week 16 Picks and Predictions: Trampled Under Taylor's Foot

The Indianapolis Colts are off to the desert to take on the Arizona Cardinals in Week 16 of the NFL season on Saturday. The Colts have been playing some inspired football of late while the Cardinals have lost consecutive games they probably shouldn’t have against the Rams and especially the lowly Lions. 

This is the second of two games taking place on Christmas Day and it should be a very competitive matchup if both teams bring their A games. NFL betting lines opening with Arizona as a 1.5-point home favorite before moving to -3 on Saturday afternoon.

Is Santa going to reward the Cards for being good this year or will Indianapolis dump coal in their stocking? We let you know what we think with our best free Colts vs. Cardinals betting picks and prediction…